psoriasis treatment,Psoriasis is an immune mediated , chronic, non contagious skin disorder characterized by scaling and inflammation due to increased cell growing, that can develop on virtually any part of the body, even the nails and scalp.
Normally, skin cells grow gradually and flake off about every 4 weeks, replacing with new cells. In psoriasis, new skin cells move rapidly to the surface of the skin, within a week.
The pathogenetic pathway involves various immunocytes and immune molecules. Activated Tcells will trigger a chain of cellular and molecular reactions leading to the formation of psoriatic lesions. Although the roles of T cells in psoriasis have been confirmed, the exact mechanisms of psoriasis and the origin of abnormal T cells are still unclear. A variety of other immune abnormalities such as B cells, monocytes, neutrophils and erythrocytes are also seen in action.
Typical characteristics of psoriasis are red, dry, elevated plaques of skin. Psoriasis is not contagious
Causes And Risk Factors
. Family history of psoriasis
.An Injury to the Skin
Plaque psoriasis–Areas are red at the base and covered by silvery scales.
Guttate psoriasis–Small, drop-shaped lesions appear on the trunk, limbs, and scalp. Most often triggered by upper respiratory infections
Pustular psoriasis–Blisters of noninfectious pus appear on the skin. Attacks of pustular psoriasis may be triggered by medications, infections, stress, or exposure to certain chemicals.
Inverse psoriasis–Smooth, red patches occur in the folds of the skin near the genitals, under the breasts, or in the armpits. The symptoms may be worsened by friction and sweating.
Erythrodermic psoriasis–Reddening and scaling of the skin, often seen with severe sunburn or to taking corticosteroids (cortisone) or other medications. It can also be caused by a prolonged period of increased activity of psoriasis that is poorly controlled.
Psoriatic arthritis –Joint inflammation that produces symptoms of arthritis in patients who have or will develop psoriasis. It causes swelling and pain in joints-most often in the fingers and toes-in an irregular pattern that may be different on opposite sides of the body.